Which of the following assessment findings in a patient's health history supports a diagnosis of substance dependence?

Substance dependence is characterized by the need to continually use the substance in order to avoid unpleasant physical symptoms of withdrawal (physical dependence), often accompanied by an intense craving for the substance (psychological dependence). Problems related to substance use tend to become more serious with repeated use. Answers 1, 3, and 4 are behavior-related. Answer 2 demonstrates a physical finding.