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Question:
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.Oral dosage form of medication that can usually be crushed or chewed if needed is immediate-release. Extended-release, sustained-release, and other special-release formulations should not be crushed or chewed, because the drug will release all immediately instead of slowly or overtime as intended. Orally disintegrating tablets should not be crushed or chewed either, because they are intended to be absorbed through the buccal mucosa. Finally, enteric-coated formulations, such as that of aspirin, may irritate the gastric mucosa if chewed or crushed instead of swallowed whole. The Institute for Safe Medication Practices retains a list of medications that should not be crushed or chewed.
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