When the prescriber indicates dispense as written on the prescription, how should a prescription be filled?

The prescriber wants the prescription filled exactly as written, with the brand name drug when dispense, as written, is indicated. Dispense as written only comes into play in real-world applications when the prescriber wants only a brand-name drug. Because the point of dispense as written is to stop the automatic substitution to a generic drug, a prescription would not be written "dispense as written" for a generic drug.