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Which applications require the use of a host application for replication?

A Virus

Computer viruses infect a wide range of subsystems on their hosts. A computer virus is a type of malware that, when activated, multiplies itself by replicating itself or infects other programs by changing them. In addition to computer applications, data files and the hard drive's boot sector might be infected. When this replication is successful, the afflicted regions are referred to be "infected."