What is the major difference between matter at the nanoscale and matter at larger scales such as millimeters or inches?

Nanotechnology is the science of studying very small pieces of matter. A nanometer is bigger than an atom, but smaller than a millimeter. The author explains that matter at the nanoscale and matter at larger scales both have different and special characteristics: "At the nanoscale, the physical, chemical, and biological properties of materials differ from the properties of matter either at smaller scales, such as atoms, or at larger scales that we use in everyday life such as millimeters or inches."